First impressions !
Send your CV in a good quality, A4 sized, thick brown envelope, also always use the cardboard backed type. They are slightly more expensive, will ensure that your CV arrives in tip-top condition and most importantly, because they are more difficult to fit into the average office waste paper bin, (usually needing to be ripped in two first), the prospective employer will keep your CV on his desk for longer. Use a printed Address label on the front ( placed exactly in the middle ) . Don't put a sender address on the envelope either, this ensures he/she has to actually open your envelope to see what it is and who it's from, basically you are trying to force them to read your CV
Use good quality paper to print your CV onto. I always use slightly textured (laid) Conquerer 100gsm paper in brilliant white. I have my CV on a floppy and if i ever need to send it out I get it printed at a local print/copy shop in town using their laser printer. I even ensure that the paper watermark is the correct way up ! (attention to detail).
Although I am not an employer myself, if anybody does send in any speculative letters or CV's for potential jobs at my workplace they certainly pass through my hands for comment or opinions, the first things that gets noticed are any obvious spelling mistakes, or glaring grammatical errors. It shows a lack of attention to detail and these CV's usually take the shortest route to the bin. As my own spelling, grammar and puntuation can be sub standard at times i have used a proffesional CV writing agency in the past to proof read and correct my CV. Most of my writing at work is wrtten in capital letters, purely for clarity, you soon forget where you should and shouldn't use capitals and even puntuation marks after a few years of this style of writing, hence getting the pro's in. 5 years ago I got my current job after using this service, a tenner well spent in my opinion.
Having a decent CV won't get you a job, it may well get you an interview though which is where you get the job. If you send in a shabby CV you will never get through that door, good luck......