Maybe it is about time I posted something Mr. A. Nonymouse commented -

Due to the crystalline structure created during drawing and the fact that signals travel not through wire (electrons are way too slow moving) but as a EM wave around the wire, it  may potentially be "directional", in other words, it may effect the EM wave differently depending on the direction of the crystal boundaries and the direction the wave travels.

 

As a result, of course, ALL DRAWN WIRE would be "directional".

 

It may or may not be a real, audible effect or non, that is a separate issue.

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Given what Tones said about the way copper forms I am not sure what to think. I would probably trust Tones as he works in the field.